The Global Economy and Development Program at Brookings conducted a survey on multilateralism in the Spring of 2021 as part of a project on the future of global governance. This report summarizes and analyzes the results. It comes at a time when the new Biden administration has re-committed the United States to multilateral cooperation and multiple initiatives—notably on international taxation, the issuance of $650 billion of new Special Drawing Rights (SDRs), and ramped up efforts to cut emissions to combat climate change—are underway. At the same time, the rivalry between the United States and China is growing, threatening a new form of Cold War, and new technologies are emerging, promising enhanced human welfare while introducing the risk of misuse. The COVID-19 pandemic is still far from under control in most developing countries due to a lag in vaccination rates and the uneven recovery from the pandemic-induced economic recession.